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KMID : 0942820060050020107
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Journal of Korean Brain Tumor Society
2006 Volume.5 No. 2 p.107 ~ p.111
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Cystic Germinoma in the Basal Ganglia Treated by Chemotherapy Alone - Case Report -
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Shim Jae-Hyone
Kim Ki-Uk
Kim Dae-Chul
Kim Jae-Suk
Choi Sun-Seob
Song Young-Jin
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Abstract
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Germinoma arising in the basal ganglia is a rare, well-documented entity representing 5% to 10% of all intracranial germinomas. And it has been known that the germinoma of the basal ganglia is usually associated with cystic formation on brain CT and MRI findings. We report a case of cystic germinoma in the basal ganglia. Although pure germinoma in the basal ganglia is generally radiosensitive and potentially curable, we have chosen chemotherapy alone in order to prevent late sequelae of radiotherapy. The patient began to receive chemotherapy without radiotherapy. After eight cycles of treatment every 4 weeks, the patient displayed a nearly complete response and was improved. No neurologic sequelae was seen at discharge. Follow-up brain CT showed no residual enhancing lesion. The patient was asymptomatic for 2 years follow-up.
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KEYWORD
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Germinoma, Basal ganglia, Chemotherapy, Cystic
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